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A REVOLUTIONARY APPROACH TO PARTICLE CHARACTERIZATION

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    Praise for Total Holographic Characterization:

    "THC shows a significant superiority to FI and RMM in detecting heterogenous protein aggregates which often appear as transparent and porous particles."

    FROM: The Journal of Pharmaceutical Sciences, The Strengths of Total Holographic Video Microscopy in Detecting Sub-Visible Protein Particles in Biopharmaceuticals: A Comparison to Flow Imaging and Resonant Mass Measurement

    Harri Rahn*, Merve Oeztuerk, Nikolai Hentze, Friederike Junge, Markus Hollmann

    AbbVie Deutschland GmbH & Co. KG, Knollstraße, Ludwigshafen 67061, Germany

    "In this study, three techniques, including Raman microscope, BMI and THC, were screened to monitor the formation of FFA particles in placebo solution. The results indicated THC is the most suitable one, featuring high sensitivity, minimal interruption to samples and low interference from formulation matrices."

    FROM: European Journal of Pharmaceutics and Biopharmaceutics, Screening Techniques for Monitoring the Sub-visible Particle Formation of Free Fatty Acids in Biopharmaceuticals

    Wei Chen, Denis Klemm, Kathrin Gregoritza, Ravuri Satya Krishna Kishore, Jan Olaf Stracke, Christine Wurth, Cosimo Pinto, Nuria Sancho Oltra

    F. Hoffmann-La Roche AG, Grenzacherstrasse 124, 4070 Basel, Switzerland

    Spheryx, with its revolutionary technique Total Holographic Characterization®, delivers solutions that provide a new window into suspensions at the sub-visible level.

    Suspensions are a part of our daily lives from electronics, pharmaceuticals and industrial fluids to water quality, cosmetics, chemicals and petroleum products. All of these products must be analyzed throughout the development, manufacturing and quality assurance processes to ensure product quality and consistency.

    Spheryx provides capabilities, never before possible, to develop and monitor products and provide improved information and control. The results will be better, more effective products, less waste, and increased efficiency, producing cost savings and improved market share.

    Semiconductor Manufacturing
    Biologic Pharmaceuticals
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    Water Quality
    Consumer Products

    Upcoming Appearances

    IFPAC 2024

    March 3-6, 2024
    Bethesda, MD

    Learn more here: https://ifpacglobal.org/

    2024 Biotherapeutics and Vaccines Development Gordon Research Conference

    March 17-22, 2024
    Galveston, TX

    Learn more here: https://www.grc.org/biotherapeutics-and-vaccines-development-grs-conference/2024/

    5th Engineering Cosmetics and Consumer Products Conference

    April 22-24, 2024
    Philadelphia, PA

    Learn more here: https://www.aiche.org/conferences/conference-on-engineering-cosmetics-and-consumer-products/2024

    APV Biopharma Stability & Cold Stability for Biologics/Therapeutic Proteins including novel formate, Vaccines, Cell Therapies and mRNAs

    May 14-15, 2024
    Lisbon, Portugal

    Learn more here: https://www.apv-mainz.de/no_cache/en/seminare/events/event/seminar/6981/

    245th Electrochemical Society Meeting

    May 26-30, 2024
    San Francisco, CA

    Learn more here: https://www.electrochem.org/245

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